top of page

Research Projects

We are mainly focusing of the physiology and pathology of the retina and choroid. Our research includes  vascular biology, neurobiology, regenerative medicine, gene therapy, and stem cell biology.

  • YH Yoon's Projects

    • Restoration of lysosomal acidification as a treatment target for dry AMD: Modulation of zinc and phosphodiesterase.​

    • Investigation about the mechanism of and treatment for tamoxifen-induced maculopathy with focus on Müller cells

    • Modulation of zinc as a target for the development of treatment strategies for retinal cell death in retinal detachment 

  • JY Lee's Projects

    • Development of 3D soft implant tissues with hypo-immunogenicity

    • Study on ocular control mechanisms modulated by expression of protein for the development of new therapeutics for uveitis

    • Pilot Study on the Effect of Gene Therapy in Retinitis Pigmentosa Animal Model

    • Computational polarization microscopy for large-area high-resolution retinal birefringence imaging in vivo

  • J Lee's Projects

    • Physiological significance of pericytes in the maintenance of choroidal blood vessels. 

    • Physical and chemical property of retinal blood vessels reflecting systemic disease.

    • Early treatment for diabetic retinopathy by regulating pericytes.

    • Distinctive roles of pericytes and smooth muscle cells  in the choroid.

    • Endothelial ultrastructure and its functional significance in the choroidal blood vessels.

    • Organotypic regulation of vascular ultrastructure by endothelial PLVAP.

    • Therapeutic approach for AMD by preserving healthy choroid and RPE.

    • Exsomal small RNA profiling for vision-threatening retinal diseases.

    • Potential therapeutic effect of DX2 on AMD.

  • YJ Kim's Projects

    • a​

    • b

    • c

Wooden Hut
bottom of page